Flagyl uses and contraindications

Symptomatic and asymptomatic Trichomoniasis:bacteria2
Flagyl is indicated for the treatment of symptomatic and asymptomatic trichomoniasis in adult patients.

The medication is used in both sexual partners to prevent the reinfection in both partners.
Flagyl is used as a therapy for acute intestinal amebiasis (amebic dysentery) and amebic liver abscess.

Anaerobic bacterial infections:
6Flagyl effectively treats serious infections due to susceptible anaerobic bacteria. The medication is used with surgical procedures.

Flagyl is prescribed to treat intra-abdominal infectious disease such as peritonitis, intra-abdominal abscess, and liver abscess, caused by susceptible bacteria.

In the treatment of skin infections the medication is indicated to be used to cure and prevent diseases caused by Bacteroides and Fusobacterium species.

The medication works effectively for gynecologic infections such as endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection.

The other medical uses of the medication include: bone and joint infections, central nervous system infections (including meningitis and brain abscess), lower respiratory tract infections such as pneumonia, empyema, and lung abscess and others.7
Flagyl is not used in breast-feeding women and in patients with hypersensitivity and allergic reactions to metronidazole or other nitroimidazole agents. The medication is contraindicated in women in the first trimester of pregnancy.

Pregnancy warnings

Metronidazole use in pregnant women during the first trimester is contraindicated. The use of this medicine in pregnant women during the second and third trimesters is controversial.
Clinical studies were not held in such women, animal studies have shown no side effects the fetus. Still the use of this antibiotic in pregnant women should be carefully evaluated by a doctor.

8Breastfeeding Warnings

Metronidazole is found in human milk at levels which put the nursing babies at risk. So the treatment with the medicine should be discontinued or the breast-feeding should be stopped for the period of treatment with this medicine.

Those women, who breastfeed their babies and need to take single dose of Metronidazole, can pump their milk and store it for feeding their babies.

Generally as the medicine is excreted in human milk its use is not recommended.
Still in some cases the risk for breastfeeding women and infants should be estimated carefully. Sometimes, doctors suggest using this medicine as the benefit of the treatment is higher than potential risk.

Metronidazole contraindications

Any hypersensitive reaction to Metronidazole should be considered as a risk factor for having severe allergic reaction to this medicine, the medicine should not be adjusted in such cases.9

To avoid side effects related to Metronidazole treatment, one should follow his/her doctor’s advice and use the proper dose.

The use of alcohol is absolutely contraindicated. Alcohol should be avoided during the treatment and within 3 days after the treatment is stopped.

10Metronidazole cautions

Prolonged treatment with Metronidazole may increase the chance of occurrence of such negative effects as seizures, aseptic meningitis and other side effects.

Chronic Metronidazole therapy is not recommended.

Severe hepatic impairment demands using lower doses of the medicine. The doctor’s regular monitoring of such patients is needed.

Caution and special care is required for patients with kidney disease, blood disorders, heart failure, liver disease, and other serious diseases.

Patients with allergic reactions to Metronidazole should discontinue the treatment right away when the first symptoms of allergy appear. Any worsening of the health conditions during the treatment with this medicine should be reported to a doctor.

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